Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Zeposia Initiation Pack (Ozanimod).

Blood pressure: Zeposia Initiation Pack (Ozanimod) may increase blood pressure and is not recommended for people who have uncontrolled high blood pressure. If you have high blood pressure, discuss with your doctor how Zeposia Initiation Pack (Ozanimod) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zeposia Initiation Pack (Ozanimod), and whether any special monitoring is needed.

Additionally, foods with a high tyramine content are known to interact with Zeposia Initiation Pack (Ozanimod), which can cause severe increases in blood pressure. People taking Zeposia Initiation Pack (Ozanimod) should avoid aged, fermented, cured, smoked, and pickled foods. Examples included aged cheeses, smoked or pickled fish, processed meats and sausages, and yeast extracts. In particular, avoid meat, fish, or daily products that may have undergone protein breakdown by aging, pickling, fermentation, or smoking to improve flavour.

Cancer: Medications such as Zeposia Initiation Pack (Ozanimod) may increase your risk for certain cancers, particularly skin cancer. Your doctor will monitor you for skin cancer while you are taking Zeposia Initiation Pack (Ozanimod). Report any changes to your skin, such as change in size, colour, or shape of moles, to your doctor as soon as possible.

Depression: People with MS often experience depression more often than the general public. Zeposia Initiation Pack (Ozanimod) may contribute to the symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Zeposia Initiation Pack (Ozanimod) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zeposia Initiation Pack (Ozanimod), and whether any special monitoring is needed.

If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or notice them in a family member who is taking Zeposia Initiation Pack (Ozanimod) contact your doctor as soon as possible.

Eye problems: People who have Diabetes or a history of inflammation of the middle of the eye are at an increased risk of developing swelling in the macula of the eye. It is recommended that you have an eye examination after taking Zeposia Initiation Pack (Ozanimod) for 3 or 4 months to check for changes in your eyes that have not caused symptoms. Report any changes in vision to your doctor as soon as possible.

Heart problems: Zeposia Initiation Pack (Ozanimod) causes a decrease in heart rate a few hours after taking the first dose. Your doctor will want to check your heart before you start Zeposia Initiation Pack (Ozanimod). You may be asked to stay at your doctor's office or clinic for 6 hours after your first dose to allow the doctor to monitor your heart rate and treat any problems before they become an emergency. It may be necessary to be monitored for a longer period of time if you develop very low heart rate or an irregular heartbeat.

If you have a heart problem, discuss with your doctor how Zeposia Initiation Pack (Ozanimod) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zeposia Initiation Pack (Ozanimod), and whether any special monitoring is needed.

Infections: Zeposia Initiation Pack (Ozanimod) works by decreasing the number of white blood cells in the blood stream. White blood cells are responsible for fighting infection in the body. As a result, people taking Zeposia Initiation Pack (Ozanimod) may have an increased risk of infections. If you notice signs of an infection, such as fever, redness, or swelling, contact your doctor as soon as possible. Zeposia Initiation Pack (Ozanimod) stays in your body for about 3 months after you stop taking it, so you will continue to be at risk of infection during this time.

Liver function: People taking Zeposia Initiation Pack (Ozanimod) may have changes in liver function that produce abnormal liver test results. Your doctor will recommend regular liver tests while you are taking Zeposia Initiation Pack (Ozanimod). If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Progressive multifocal leukoencephalopathy (PML): There have been reports of PML after using Zeposia Initiation Pack (Ozanimod). PML is a rare viral infection that causes nerve damage in the brain. If you experience memory loss, vision changes, trouble thinking, personality changes, or difficulty walking, contact your doctor immediately.

Posterior Reversible Encephalopathy Syndrome (PRES): This is a rare disease of the brain that may occur when using Zeposia Initiation Pack (Ozanimod). If you have had a previous episode of PRES, this may not be an appropriate medication for you. Make sure your doctor knows you have experienced this before. If you experience signs and symptoms of PRES, such as headache, nausea, vomiting, seizures, change in awareness or consciousness, or vision changes, contact your doctor immediately.

Serotonin syndrome: Severe reactions are possible when Zeposia Initiation Pack (Ozanimod) is combined with other medications that act on serotonin, such as serotonin reuptake inhibitors, medications used to treat depression, and certain migraine medications. These combinations should be avoided. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, or changes in mental state including delirium and agitation. Coma and death are possible.

Stopping Zeposia Initiation Pack (Ozanimod): Zeposia Initiation Pack (Ozanimod) works while it is being taken properly. Because it stays in the body for a long period of time, you may experience the benefit of having taken Zeposia Initiation Pack (Ozanimod) for several weeks after stopping. After that, symptoms of MS may return and be more severe than before starting to take Zeposia Initiation Pack (Ozanimod). Speak to your doctor before stopping Zeposia Initiation Pack (Ozanimod).

Vaccines: Talk to your doctor to determine whether you need any vaccines before starting treatment. During and for up to 3 months after stopping treatment you should avoid any vaccines containing live viruses.

Pregnancy: Zeposia Initiation Pack (Ozanimod) may cause harm to an unborn fetus and should not be used during pregnancy. If you become pregnant while taking Zeposia Initiation Pack (Ozanimod), contact your doctor immediately. Women who could become pregnant who are taking Zeposia Initiation Pack (Ozanimod) should use an effective method of birth control (e.g., birth control pill, condoms) during treatment, and for 3 months after stopping treatment with Zeposia Initiation Pack (Ozanimod).

Breast-feeding: It is not known if Zeposia Initiation Pack (Ozanimod) passes into breast milk. If you are breast-feeding and are taking Zeposia Initiation Pack (Ozanimod), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Zeposia Initiation Pack (Ozanimod) have not been established for children.