Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Sotalol. If you are concerned about side effects, discuss the risks and benefits of Sotalol with your doctor.

The following side effects have been reported by at least 1% of people taking Sotalol. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal pain
• anxiety
• decreased sexual ability
• Diarrhea
• difficulty sleeping
• dizziness or lightheadedness
• itching of skin
• loss of appetite
• nausea or vomiting
• nervousness
• numbness or tingling of fingers or toes
• unusual tiredness or weakness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• back or joint pain
• breathing difficulty or wheezing
• Depression
• fainting
• Fever and sore throat
• Low Blood Pressure
• shortness of breath
• skin rash
• slow heartbeat (especially less than 50 beats per minute)
• swelling of ankles, feet, or lower legs
• unusual bleeding or bruising
• vision problems

Stop taking the medication and seek immediate medical attention if any of the following occur:

• chest pain
• fast or irregular heartbeat
• signs of a Anaphylaxis (severe allergic reaction), e.g.:
  • Hives
  • shortness of breath
  • swelling of the lips, tongue, or throat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Sotalol.

80 mg
Each blue, capsule-shaped, biconvex tablet, identified "APO-80" on one side and scored on the other, contains sotalol HCl 80 mg. Nonmedicinal ingredients: colloidal silicon dioxide, dextrates, FD&C Blue No. 2 Aluminum Lake, magnesium stearate, and methylcellulose.

160 mg
Each blue, capsule-shaped, biconvex tablet, identified "APO-160" on one side and scored on the other, contains sotalol HCl 160 mg. Nonmedicinal ingredients: colloidal silicon dioxide, dextrates, FD&C Blue No. 2 Aluminum Lake, magnesium stearate, and methylcellulose.

Do not take Sotalol if you:

• are allergic to sotalol or any ingredients of the medication
• have a severely slow heart rate
• have Allergic Rhinitis
• have Asthma or severe chronic obstructive respiratory diseases (e.g., emphysema, chronic Bronchitis)
• have long QT syndrome
• have low potassium levels in the blood
• have serious heart block (second- and third-degree AV block), unless a functioning pacemaker is present
• have severe or uncontrolled Congestive Heart Failure
• have severe sinus node dysfunction
• have sick sinus syndrome

Do not give Sotalol to people in cardiogenic shock.

There may be an interaction between sotalol and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Sotalol. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Sotalol.

Abnormal heart rhythm: Sotalol may cause a heart rhythm disturbance called QT prolongation. It can also worsen or trigger an irregular heart beat (arrhythmia). You doctor will monitor your heart rhythm regularly while you are taking Sotalol with a test called an electrocardiogram (ECG).

Congestive heart failure: If you have congestive heart failure, discuss with your doctor how Sotalol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Sotalol, and whether any special monitoring is needed.

Diabetes: The signs of low blood sugar may not be as noticeable when taking sotalol. If you have diabetes and take insulin or other medications that work by reducing blood sugar levels, you should monitor blood sugar carefully while taking Sotalol. Discuss with your doctor how Sotalol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Sotalol, and whether any special monitoring is needed.

Electrolyte levels: People with low potassium or magnesium levels should not use sotalol until these imbalances are corrected, as these conditions can create higher risk for abnormal heart rhythms with the use of Sotalol.

Hyperthyroidism (high level of Thyroid hormones): Sotalol may reduce the symptoms of hyperthyroidism, giving a false impression of improvement. Stopping the medication suddenly could worsen hyperthyroidism. If you have hyperthyroidism, discuss with your doctor how Sotalol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Sotalol, and whether any special monitoring is needed.

Kidney function: Sotalol passes from the body via the kidneys. If you have reduced kidney function, discuss with your doctor how Sotalol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Sotalol, and whether any special monitoring is needed.

Lung problems: People with asthma and certain other lung problems (e.g., chronic bronchitis, emphysema) should not take sotalol.

Severe allergies: If you have allergies severe enough to cause anaphylaxis (a severe allergic reaction where swelling of the face, lips, and throat make it difficult to breathe), you should talk to your doctor about what to do if you have an allergic reaction. Sotalol may make it more difficult to treat your allergic reaction with Epinephrine.

Stopping the medication: Stopping Sotalol suddenly can cause abnormal heart rhythms, chest pain (Angina), and even Heart Attack. Do not suddenly stop taking Sotalol. Consult your doctor about how to safely stop taking Sotalol.

Surgery: If you are scheduled for surgery, inform all doctors involved in your care that you are taking sotalol.

Pregnancy: Sotalol should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Sotalol, contact your doctor immediately.

Breast-feeding: Sotalol passes into breast milk. If you are a breast-feeding mother and are taking sotalol, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children and adolescents: The safety and effectiveness of using sotalol have not been established for children and adolescents under 18 years of age.

Sotalol belongs to the classes of medications called antiarrhythmics and beta-blockers. It is used to treat certain types of abnormal heart rhythms (Arrhythmias). It works by changing how electrical impulses affect the heart muscle and by helping the heart to beat more regularly.

Your doctor may have suggested Sotalol for conditions other than those listed in these drug information articles. As well, some forms of Sotalol may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Sotalol, speak to your doctor. Do not stop taking Sotalol without consulting your doctor.

Do not give Sotalol to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Sotalol if their doctor has not prescribed it.