Azathioprine belongs to the group of medications known as immunosuppressive agents. It is used to prevent the rejection of kidney transplants and to treat severe Rheumatoid Arthritis that is not responding to conventional treatment.
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Tablet, Professional Service, Suspension
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Apotex, Pro Doc Limitée, Teva
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Azathioprine is available in tablet and injectable form.
When used to prevent kidney transplant rejection, azathioprine is usually started on the day of transplant with an intravenous (into the vein) injection. The initial dose is based on body weight at 3 to 5 mg per kilogram of body weight daily. After the transplant, tablets are used. The dose is then generally reduced to a maintenance dose of 1 mg to 3 mg per kilogram of body weight per day.
For treatment of rheumatoid arthritis, azathioprine is usually given at a dose of approximately 1 mg per kilogram of body weight (50 mg to 100 mg) per day by mouth, in a single daily dose or on a twice-daily schedule. After 6 to 8 weeks, your doctor may increase your dose by 0.5 mg per kilogram daily if needed. Additional increases may be prescribed by your doctor every 4 weeks up to the maximum daily dose of 2.5 mg per kilogram per day.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Azathioprine exactly as prescribed by your doctor. If you miss a dose and you are taking the pills once a day, do not take the missed dose at all, but go back to your regular dosing schedule.
If you are taking pills more than once a day, skip the missed dose and go back to your regular schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Azathioprine at room temperature, protect it from light, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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