Kalydeco (Ivacaftor) belongs to the class of medications called Cystic Fibrosis transmembrane conductance regulator (CFTR) potentiators. It is used to treat cystic fibrosis (CF) in adults and children over the age of 2 who have one of several possible mutations (a change) in their CFTR gene.
Available form
Tablet, Granules
Manufacturer
Vertex
Dosage
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The usual dose for adults and children (over the age of 6 years and weighing more than 25 kg), is 150 mg twice a day (morning and evening about 12 hours apart) with a fat-containing food. Fat-containing food helps get the right amount of medication into your body. Examples include meals or foods prepared with butter or oils, eggs, cheeses, nuts, whole milk, or meats. Meals and snacks recommended in CF guidelines contain the right amounts of fat.
The usual dose for children between the ages of 2 years and 6 years is based on body weight. Oral granules are available for children ages 2 years and older, or individuals who have difficulty swallowing tablets. The granules may be sprinkled on soft foods or liquids (excluding grapefruit juice) and consumed within 1 hour. The granules should be consumed with or immediately after a fat-containing food.
Tablets should be swallowed whole with fluids and not chewed, crushed, or dissolved.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that Kalydeco (Ivacaftor) be taken exactly as prescribed by your doctor.
If you miss a dose by less than 6 hours, take the missed dose with fat-containing food, and continue with your regular schedule. If you miss a dose by 6 or more hours, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Kalydeco (Ivacaftor) at room temperature, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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