Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Eligard (Leuprolide).

Anemia: Reduced testosterone levels contribute to low levels of red blood cells. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, pale skin, or feeling unusually tired, contact your doctor as soon as possible.

Your doctor will do blood tests regularly to monitor the number of specific types of blood cells, including red blood cells, in your blood.

Depression: Changed levels of hormones in the body have been known to cause mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Eligard (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Eligard (Leuprolide), and whether any special monitoring is needed.

If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, or decreased interest in activities, or notice them in a family member who is taking Eligard (Leuprolide),contact your doctor as soon as possible.

Diabetes: Eligard (Leuprolide) may cause a loss of blood glucose control, and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Eligard (Leuprolide).

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Eligard (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Eligard (Leuprolide), and whether any special monitoring is needed.

Heart problems: Eligard (Leuprolide) may increase the risk of heart problems such as changes in heart rhythm. You may be more at risk of experiencing heart problems if you have congenital long QT syndrome, electrolyte (e.g., potassium) abnormalities, or Congestive Heart Failure, or you are taking medications that affect heart rhythm (e.g., quinidine, procainamide, Amiodarone, Sotalol, Flecainide). Discuss with your doctor how Eligard (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Eligard (Leuprolide), and whether any special monitoring is needed.

Medical conditions: If you have urinary tract obstruction (a blockage in the urinary tract), reduced kidney or liver function, spinal cord compression, or cancer that has spread to the bones of the spine, discuss with your doctor how Eligard (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Eligard (Leuprolide), and whether any special monitoring is needed.

Men and the heart: There may be an increased risk of heart-related events (e.g., heart attacks, stroke, heart-related death) in men being treated for prostate cancer with GnRH medications. Before you start treatment, tell your doctor if you have diabetes, heart disease, had a previous heart attack or stroke, or have cardiovascular risk factors (e.g., high blood pressure, smoking, or cholesterol). If you have any of these conditions, discuss with your doctor how Eligard (Leuprolide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Eligard (Leuprolide), and whether any special monitoring is needed.

Osteoporosis: Eligard (Leuprolide) can cause the bones to lose thickness. Your doctor will monitor you for this while you are using Eligard (Leuprolide). If you have osteoporosis or are at risk for it (e.g., have been smoking or drinking excessive amounts of alcohol for a long time, have a family history of osteoporosis, or are taking medications such as Prednisone or anti-seizure medications), discuss with your doctor how Eligard (Leuprolide) may affect your medical condition and whether any special monitoring is needed.

Starting treatment: During the first week of treatment with Eligard (Leuprolide), you may notice that your signs and symptoms temporarily get worse. This is due to a sudden increase in hormones that will normalize once the right dose for you has been found.

Pregnancy: Eligard (Leuprolide) should not be used during pregnancy. Eligard (Leuprolide) is not recommended for use by women.

Breast-feeding: It is not known if Eligard (Leuprolide) passes into breast milk. Eligard (Leuprolide) is not recommended for use by women.

Children: The safety and effectiveness of using Eligard (Leuprolide) have not been established for children under 12 years of age.