Stelara (Ustekinumab) belongs to the class of medications called selective immunomodulating agents, also known as biologics. It is used to treat chronic, moderate-to-severe plaque psoriasis for adults who are candidates for phototherapy or systemic therapy.
Available form
Injectable
Manufacturer
Amgen, Janssen
Dosage
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To treat adults with either plaque psoriasis or psoriatic arthritis, the usual dose is 45 mg injected under the skin. The dose is repeated in 4 weeks, and then every 12 weeks thereafter. For people who weigh more than 100 kg, a dose of 90 mg may be used. When treating plaque psoriasis, some people may need to receive Stelara (Ustekinumab) every 8 weeks. The dose may be injected on top of the thigh or around the abdomen (about 2 inches away from the belly button).
For treating children and adolescents 6 to 17 years of age with plaque psoriasis, the dose is based on body weight.
For the treatment of Crohn's disease and ulcerative colitis, the first dose is given as an intravenous (into a vein) infusion and the dose is based on body weight. The dose is repeated as an injection under the skin 8 weeks after the first dose. The usual maintenance dose is 90 mg every 8 weeks. Under certain conditions, your doctor may decrease the frequency of your injections to once every 12 weeks.
Most people using Stelara (Ustekinumab) can be trained by a health care professional to give themselves the injection. Stelara (Ustekinumab) is used with the guidance and supervision of a doctor. Your doctor or nurse will assist you in the preparation and injection of your first dose (or first few doses). Do not attempt to inject Stelara (Ustekinumab) on your own until you completely understand how to inject a dose.
Follow the instructions from your doctor or pharmacist when administering the medication. The solution should be colourless or slightly yellow and may contain a few small clear or white particles of protein. Do not use the injection if it appears cloudy or discoloured, or if you see other particles floating in it. After taking the medication out of the refrigerator, preparing the syringe, and choosing the injection site, inject the dose under the skin as instructed by your health care provider.
Use a different site for each injection to decrease the risk of skin irritation. Dispose of your used needles in an appropriate sharps container.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important that Stelara (Ustekinumab) be given exactly as recommended by your doctor. If you miss a dose, contact your doctor for advice. Do not inject a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Stelara (Ustekinumab) in the refrigerator in its original carton, protect it from light, and keep it out of the reach of children. If necessary, pre-filled syringes may be kept at room temperature for up to 30 days. Once a syringe has been stored at room temperature, it should not be returned to the refrigerator. Do not freeze or shake the medication.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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