Siliq (Brodalumab) belongs to the class of medications called biological response modifiers ("biologics"). It is used to treat moderate-to-severe plaque psoriasis in adults whose specialists have determined that systemic or phototherapy may be beneficial.
Available form
Injectable
Manufacturer
Bausch Health
Dosage
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The recommended starting dose of Siliq (Brodalumab) is 210 mg injected subcutaneously (under the skin) once a week for 3 weeks. After 3 doses, the recommended dose is 210 mg injected every 2 weeks. Each dose is given as a single injection of 210 mg (1.5 mL). Each syringe is single-use only and should be safely discarded after injecting the dose.
Siliq (Brodalumab) is administered by subcutaneous injection in the thigh, abdomen, or outer upper arm. It is important to rotate the site of injection. Avoid injecting into areas that are tender, bruised, red, hard, or affected by psoriasis.
Do not shake Siliq (Brodalumab) before using it. The solution for injection should be clear to slightly opalescent, and colourless-to-slightly-yellow. If it is cloudy or you can see lumps, flakes, or coloured particles in the solution, do not use it. To minimize discomfort, allow Siliq (Brodalumab) to warm to room temperature for 30 minutes before injecting.
If you are using Siliq (Brodalumab) at home, your doctor will ensure that you understand exactly how to use it. Make sure you ask any and all questions necessary to ensure that you use it exactly as prescribed. It is important to visit your doctor regularly during therapy to ensure that the medication is working safely and effectively.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Siliq (Brodalumab) exactly as prescribed by your doctor.
If you miss a dose, inject it as soon as possible. Then talk to your doctor about when you should inject the next dose. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Siliq (Brodalumab) in the refrigerator, protect it from light and moisture, and keep it out of the reach of children. Do not allow Siliq (Brodalumab) to freeze. Siliq (Brodalumab) may also be kept at room temperature in its original carton for up to 14 days.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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