Simulect (Basiliximab) belongs to the group of medications known as immunosuppressants. It is used to prevent the rejection of a transplanted kidney during the first 4 to 6 weeks after the transplant.
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Novartis Pharmaceuticals
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The dose of Simulect (Basiliximab) is 20 mg and is given as an injection or infusion into a vein.
Normally, you will be given two doses of Simulect (Basiliximab). The first dose is given just before your transplant operation starts, and the second dose is given 4 days after the operation. A doctor or nurse will give the treatment, since it has to be injected into a vein.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications.
Simulect (Basiliximab) should be stored in the refrigerator at 2°C to 8°C.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Simulect (Basiliximab). If you are concerned about side effects, discuss the risks and benefits of Simulect (Basiliximab) with your doctor.
The following side effects have been reported by at least 1% of people taking Simulect (Basiliximab). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Simulect (Basiliximab).
Each glass vial contains 20 mg of Simulect (Basiliximab). Nonmedicinal ingredients: disodium hydrogen phosphate, glycine, mannitol, potassium dihydrogen phosphate, sodium chloride and sucrose. Simulect (Basiliximab) does not contain preservatives.
Do not use Simulect (Basiliximab) if you are allergic to Simulect (Basiliximab), mouse cell proteins, or to any of the ingredients of the medication.
There may be an interaction between Simulect (Basiliximab) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Simulect (Basiliximab). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Allergic and infusion reactions: Simulect (Basiliximab) can cause allergic reactions and side effects that are related to receiving the infusion. Some of these reactions can be severe. If you experience shortness of breath, wheezing, fever, chills, lightheadedness, hoarseness, difficulty speaking, fainting, hives, or swelling of the face and throat while receiving Simulect (Basiliximab), tell your doctor or nurse immediately or get immediate medical attention.
If you experience a severe infusion reaction, you should not receive Simulect (Basiliximab) again.
Vaccines: People receiving Simulect (Basiliximab) may not respond as well to vaccines or may be at risk of becoming ill from a live vaccine. Talk to your doctor if you need any vaccinations while taking Simulect (Basiliximab).
Pregnancy: Simulect (Basiliximab) should not be used during pregnancy unless the benefits outweigh the risks. Women who are receiving Simulect (Basiliximab) should use adequate contraception during treatment and for 4 months following the last dose. If you become pregnant while taking Simulect (Basiliximab), contact your doctor immediately.
Breast-feeding: It is not known if Simulect (Basiliximab) passes into breast milk. If you are a breast-feeding mother and are taking Simulect (Basiliximab), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding. Women taking Simulect (Basiliximab) should not breast-feed during treatment and for 4 months after the last dose.
Children: The safety and effectiveness of using Simulect (Basiliximab) have not been established for children.
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