Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Entocort Rectal (Budesonide-rectal).

General precautions: Advise all doctors involved in your care that you have been using Entocort Rectal (Budesonide-rectal). If you have been taking "cortisone" tablets, your doctor may want you to discontinue the tablet form of the medication. Much less corticosteroid is absorbed from budesonide enemas, so stopping the tablets should be done gradually to reduce the likelihood of withdrawal symptoms such as tiredness, headache, nausea, or vomiting.

Medical conditions: People with Diabetes, Glaucoma, liver disease, Osteoporosis, or stomach ulcers should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Entocort Rectal (Budesonide-rectal), and whether any special monitoring is needed.

Severe bowel disease: People with severe ulcerative disease of the bowel should use Entocort Rectal (Budesonide-rectal) with caution, as they are susceptible to perforation of the bowel wall. If you have severe ulcerative disease, discuss with your doctor how Entocort Rectal (Budesonide-rectal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Entocort Rectal (Budesonide-rectal), and whether any special monitoring is needed.

Stopping medication: Stopping Entocort Rectal (Budesonide-rectal) suddenly may cause symptoms of the illness to return. Do not stop using Entocort Rectal (Budesonide-rectal) abruptly without checking with your doctor first.

Pregnancy: Entocort Rectal (Budesonide-rectal) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Entocort Rectal (Budesonide-rectal), contact your doctor immediately.

Breastfeeding: Entocort Rectal (Budesonide-rectal) passes into breast milk. If you are a breast-feeding mother and are using budesonide enemas, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children:  The safety and effectiveness of budesonide enemas have not been established for children.