Daunorubicin belongs to the group of cancer-fighting medicines known as antineoplastics, and specifically to the family of antineoplastics called anthracyclines. Another anthracycline is Doxorubicin.
Available form
Powder
Dosage
Manufacturer
Teva
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The recommended dose and dosing schedule of daunorubicin varies widely according to the specific disease being treated, the response to therapy, and the other medications being used. The dose administered is also based on body weight or body size. In children the administered dose is based on body weight.
Daunorubicin is usually injected into a vein through a specially prepared site on your skin. Very careful handling of Daunorubicine is required. It is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.
As well as interfering with the genetic material DNA of cancer cells, daunorubicin can interfere with some of your normal cells. This can cause a number of side effects such as hair loss and mouth sores. Keep track of any side effects and report them to your doctor as suggested in the section, "What side effects are possible with Daunorubicine?"
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Daunorubicine exactly as prescribed by your doctor.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Daunorubicine. If you are concerned about side effects, discuss the risks and benefits of Daunorubicine with your doctor.
The following side effects have been reported by at least 1% of people taking Daunorubicine. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Daunorubicine.
Daunorubicine is available as 20 mg/vial powder for solution injection.
Do not use Daunorubicine if you:
There may be an interaction between daunorubicin and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Daunorubicine.
Blood clotting: Daunorubicine can reduce the number of platelet cells in the blood. Platelets help the blood to clot, and a shortage could make you bleed more easily. Tell your doctor of any signs that your blood is not clotting as quickly. Such symptoms may include black and tarry stools, blood in the urine, easy bruising, or cuts that won't stop bleeding.
Gout and Kidney Stones: Daunorubicin may increase the levels of uric acid in the body, further increasing the risk for gout or kidney stones in people predisposed to these conditions.
Heart disease: The risk of abnormal heart rhythm, Congestive Heart Failure, and a weakened heart (cardiomyopathy) is increased in people with preexisting heart disease.
Infection: As well as killing cancer cells, Daunorubicine can reduce the number of cells in the body that can fight infection (white blood cells). Avoid contact with people with contagious infections and tell your doctor if you begin to notice signs of an infection, such as fever or chills. Discuss any vaccines with your doctor before getting vaccinated.
Pregnancy: There is a possibility of birth defect if either the man or woman is using daunorubicin at the time of conception, or if it is taken during pregnancy. Effective birth control should be practiced while using Daunorubicine. Daunorubicine may harm the baby if used during pregnancy. Tell your doctor immediately if you become pregnant while using Daunorubicine.
Breast-feeding: Women should not breast-feed while receiving daunorubicin treatment due to risk of potential harm to the infant.
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