Uptravi (Selexipag) belongs to the class of medications called prostacyclin receptor agonists. It is used alone and in combination with other medications for long-term treatment of pulmonary arterial hypertension (PAH).
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Tablet
Manufacturer
Janssen
Dosage
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The recommended starting dose of Uptravi (Selexipag) is 200 μg taken by mouth, 2 times a day. The doses should be spaced approximately 12 hours apart. Gradually, your doctor will increase your dose until you reach a dose that is effective without too many side effects. The maximum dose of Uptravi (Selexipag) is 1,600 μg taken 2 times daily.
Uptravi (Selexipag) may be taken with or without food. Taking the medication with food may reduce the severity of side effects. Swallow the tablets whole, with water. Do not split, crush, or chew the tablets.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Uptravi (Selexipag) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is less than 6 hours until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
If you miss taking your medication for 3 days or more, contact your doctor for directions on how to restart the medication. You may need to restart your treatment at a lower dose.
Store Uptravi (Selexipag) in its original package at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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