Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who uses Prostin VR (Alprostadil). If you are concerned about side effects, discuss the risks and benefits of Prostin VR (Alprostadil) with your baby's doctor.

While your baby is receiving Prostin VR (Alprostadil), health care professionals in the hospital will be monitoring your baby for any possible side effects. The following side effects have been reported by at least 1% of people using Prostin VR (Alprostadil). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if your baby experiences these side effects and they are severe or bothersome.

• apnea (episodes of regular breathing with pauses)
• Diarrhea
• Fever
• flushing
• infections
• Low Blood Pressure (symptoms include dizziness or fainting)
• slow or fast heartbeat
• spitting up
• swelling of the arms, feet, or legs

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your baby's doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abnormal heart rhythm
• Blood Clots
• blood in urine
• bluish skin colour
• convulsions or seizures
• feeling drowsy or sluggish
• hypothermia (abnormally low body temperature; e.g., shivering, shallow breathing, drowsiness, loss of consciousness)
• irritability or jitteriness
• low blood sugar levels (e.g., dizziness, lack of energy, sweating, or shakiness)
• low potassium levels (e.g., weakness, muscle cramps, Constipation, nausea or vomiting, heart palpitations, increased thirst or urination, tingling or numbness)
• stiffness

Stop the medication and seek immediate medical attention if any of the following occur:

• bleeding
• cardiac arrest
• signs of a serious allergic reaction (e.g., shortness of breath or difficulty breathing; Hives; swelling of the eyes, mouth, lips, or throat)
• troubled breathing or stopped breathing

Some people may experience side effects other than those listed. Check with your baby's doctor if you notice any symptom that worries you while your baby is on Prostin VR (Alprostadil).