The recommended adult dose of misoprostol ranges from 400 µg to 800 µg daily, taken in 2 to 4 equally divided doses (e.g., 100 µg 4 times daily, 200 µg twice daily, 200 µg 4 times daily).

Misoprostol should be taken with food or milk to reduce the risk of side effects, such as Diarrhea. Also, to reduce the risk of diarrhea, avoid antacids that contain magnesium. Antacids containing aluminum (but not magnesium) may be used to relieve symptoms such as heartburn.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Misoprostol exactly as prescribed by the doctor. Misoprostol may cause loose stools, diarrhea, and abdominal cramping while your body adjusts to it. These symptoms should go away within a few days. Do not stop the medication without first talking with your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Misoprostol at room temperature, protect it from moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.