Enbrel (Etanercept) belongs to the class of medications called biological response modifiers ("biologics") or tumour necrosis factor inhibitors (TNF blockers). It is used to treat: active ankylosing spondylitis chronic moderate-to-severe plaque psoriasis in adults moderate-to-severe juvenile idiopathic Arthritis (JIA) in children and adolescents 4 to 17 years of age who have not responded to another class of medications called disease modifying antirheumatic drugs (DMARDs) moderate-to-severe Rheumatoid Arthritis in adults Psoriatic Arthritis in adults chronic severe psoriatic arthritis in children ages 4 to 17 who are candidates for light therapy or other medications People with these conditions produce extra amounts of proteins called tumour necrosis factor (TNF), causing pain, inflammation, and damage.
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Enbrel (Etanercept) is given by subcutaneous (under the skin) injection, usually in the front of the thigh, upper arm, or abdomen. The recommended dose depends on the condition being treated.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use Enbrel (Etanercept) exactly as prescribed by your doctor. If you miss a dose of Enbrel (Etanercept), contact your doctor to find out when to take the next dose. Do not administer a double dose to make up for a missed one.
Enbrel (Etanercept) is used with the guidance and supervision of a doctor. Your doctor or nurse will assist you in the preparing and injecting your first dose (or first few doses). Do not attempt to prepare or inject Enbrel (Etanercept) on your own until you completely understand how to mix and inject a dose. If you are having difficulty giving yourself injections, talk to your health care provider.
Single-use prefilled syringes should be stored in the refrigerator at 2°C to 8°C, protected from light, and kept out of the reach of children. Do not freeze or shake. Remove the medication from the refrigerator and allow it to warm to room temperature before injecting it. This takes approximately 15 to 30 minutes.
Vials should be should be stored in the refrigerator at 2°C to 8°C and kept out of the reach of children. Do not freeze. Once mixed, vials should be stored in the refrigerator at 2°C to 8°C for up to 14 days.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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