Dacarbazine belongs to the group of cancer-fighting medications called antineoplastics. It kills cancer cells by interfering with their growth and reproduction.
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The recommended dose of dacarbazine is based on body weight or body size. The appropriate dose of dacarbazine is often given once daily for 5 or 10 days depending on the dose. After 3 weeks, the dose may be repeated if necessary.
Dacarbazine is injected into a vein through a site on your skin that has been specially prepared for this purpose. Very careful handling of Dacarbazine is required. It is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving the medication without consulting your doctor.
As well as interfering with the growth and reproduction of cancer cells, dacarbazine can interfere with some of your normal cells. This can cause a number of side effects such as hair loss and mouth sores. Dacarbazine often causes nausea and vomiting, but it is important to keep using Dacarbazine even if you feel ill, unless otherwise directed by your doctor. The feeling of nausea usually lessens within 2 days. Your doctor, nurse, or pharmacist can advise you on how to reduce the effects of nausea and vomiting. Keep track of any side effects and report them to your doctor, as suggested in the section "What side effects are possible with Dacarbazine?"
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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