Alkeran (Melphalan) belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as alkylating agents. Alkeran (Melphalan) prevents the growth of cancer cells by interfering with the genetic material DNA, which is necessary for reproduction of cells.
Available form
Tablet, Powder
Manufacturer
Aspen Pharma Trading, Auro Pharma, Eugia Pharma, Juno, Marcan Pharmaceuticals
Dosage
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Alkeran (Melphalan) is available as tablets and in an injectable form. There are many different dosing schedules used for treatment with Alkeran (Melphalan) tablets and Alkeran (Melphalan) injectable. A common adult dose of Alkeran (Melphalan) tablets for multiple myeloma is 6 mg daily for up to 2 to 3 weeks. After this time, the medication is usually stopped for a period of up to 4 weeks, and blood tests are carried out. A dose of 2 mg daily is often started on a regular basis following the waiting period.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Alkeran (Melphalan) injection will be injected by your doctor or by someone under direct supervision of your doctor. The dose is based on body size. It is usually injected into a vein through a specially prepared site on the skin. It is sometimes administered by a technique known as perfusion.
It is important to take Alkeran (Melphalan) exactly as prescribed by your doctor. Your doctor may want you to drink extra fluids while taking Alkeran (Melphalan) so that kidney problems are prevented. Alkeran (Melphalan) may cause nausea, vomiting, and loss of appetite, but it is important that you continue to use it. Do not stop taking it without talking with your doctor.
If you vomit shortly after taking a dose of Alkeran (Melphalan), call your doctor for instructions on whether to skip that dose or to take another dose. If you miss a dose of Alkeran (Melphalan), skip the missed dose and continue with your regular dosing schedule, and inform your doctor. Do not take a double dose to make up for a missed one.
As well as interfering with the genetic material DNA of cancer cells, Alkeran (Melphalan) can interfere with some of your normal cells. This can cause a number of side effects. Keep track of any side effects and report them to your doctor as suggested in the section, "What side effects are possible with Alkeran (Melphalan)?"
Store Alkeran (Melphalan) in a cool, dry place, and protect it from direct light.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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