Somavert (Pegvisomant) belongs to the group of medications called growth hormone (GH) antagonists. It is used to treat acromegaly, a condition where the body produces too much growth hormone, when other treatments, such as surgery or radiation, have not been effective or cannot be used.
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The first dose of Somavert (Pegvisomant), called a loading dose, is one dose of 40 mg given by subcutaneous (under the skin) injection. The first dose will be given by a health care professional. After this first dose, the recommended dose is 10 mg daily given by injection under the skin of the upper arm, upper thigh, stomach area, or buttocks.
Your doctor may increase or decrease the dose of Somavert (Pegvisomant) depending on the results of IGF-I (a type of hormone) levels in your blood. The maximum dose is 30 mg daily. The place of injection should be changed daily to avoid skin problems associated with repeated injection at the same site.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
If you are injecting Somavert (Pegvisomant) yourself, your doctor will show you how to use Somavert (Pegvisomant) properly. If you are not sure how to use it or have questions about how to use it, contact your doctor. Before using Somavert (Pegvisomant), thoroughly read the patient information provided and ask your doctor if you have any questions. If a caregiver will be giving you the injections, your doctor should instruct them on how to give the injection.
The injection must be given within 3 hours of preparing it. The solution for injection should be clear. If it is cloudy, discoloured, or has particles in it, do not use the injection.
It is important to use Somavert (Pegvisomant) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store the powder form of Somavert (Pegvisomant) in the refrigerator, do not allow it to freeze, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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