Propyl Thyracil (Propylthiouracil) belongs to the class of medications called antithyroid medications. It is used to treat an overactive Thyroid gland that is producing too much thyroid hormone (sometimes referred to as Hyperthyroidism).
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Paladin Labs
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The usual adult starting dose of Propyl Thyracil (Propylthiouracil) is 50 mg to 100 mg every 8 hours, with increases as necessary up to a maximum of 500 mg daily or as directed by your doctor. When doses larger than 300 mg per day are needed, the medication should be taken every 4 to 6 hours. Children's doses are based on their body weight.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose or schedule different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Propyl Thyracil (Propylthiouracil) exactly as prescribed by your doctor. Propyl Thyracil (Propylthiouracil) should not be stopped suddenly but should be withdrawn over a period of 1 to 2 months under the direction of your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Propyl Thyracil (Propylthiouracil) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Propyl Thyracil (Propylthiouracil). If you are concerned about side effects, discuss the risks and benefits of Propyl Thyracil (Propylthiouracil) with your doctor.
The following side effects have been reported by at least 1% of people taking Propyl Thyracil (Propylthiouracil). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Propyl Thyracil (Propylthiouracil).
50 mg
Each white tablet engraved with "PLB" on one side and "PPT" over score "50" on the other contains 50 mg of Propyl Thyracil (Propylthiouracil).
100 mg
Each white, round, biconvex tablet engraved with "PLB" on one side and "PPT" over score "100" on the other contains 100 mg of Propyl Thyracil (Propylthiouracil).
Do not take Propyl Thyracil (Propylthiouracil) if you:
There may be an interaction between Propyl Thyracil (Propylthiouracil) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Propyl Thyracil (Propylthiouracil). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Propyl Thyracil (Propylthiouracil).
Blood counts: Propyl Thyracil (Propylthiouracil) can decrease the number of neutrophils (a type of white blood cell that helps fight infection), red blood cells (which carry oxygen), and platelets (which help your blood to clot). If you notice any signs of infection (e.g., fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.
Hypothyroidism: Your dose of Propyl Thyracil (Propylthiouracil) will be reduced or temporarily discontinued by your doctor if signs of hypothyroidism (such as weight gain, clumsiness, and intolerance of cold temperatures) occur during treatment.
Inflamed blood vessels: Rarely, Propyl Thyracil (Propylthiouracil) can cause blood vessels to become inflamed. This inflammation can cause changes to the blood vessels, reducing blood flow and possibly causing scarring, weakening, or narrowing of the blood vessels. This can result in organ or tissue damage. If you experience any unexpected side effects, such as difficulty breathing, rash, blood in the urine, or coughing up blood, contact your doctor as soon as possible.
Kidney problems: If you have kidney problems, discuss with your doctor how Propyl Thyracil (Propylthiouracil) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Propyl Thyracil (Propylthiouracil), and whether any special monitoring is needed.
Liver function: Propyl Thyracil (Propylthiouracil) may reduce liver function and can cause liver failure. If you have liver problems, discuss with your doctor how Propyl Thyracil (Propylthiouracil) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Propyl Thyracil (Propylthiouracil), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Propyl Thyracil (Propylthiouracil).
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Size of thyroid gland: Tell your doctor if the size of your thyroid gland increases during treatment with Propyl Thyracil (Propylthiouracil). An enlarged thyroid gland is a sign that you may need a lower dose of the medication.
Pregnancy: Propyl Thyracil (Propylthiouracil) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Propyl Thyracil (Propylthiouracil), contact your doctor immediately. Women who may become pregnant should use effective birth control while taking Propyl Thyracil (Propylthiouracil).
Breast-feeding: Propyl Thyracil (Propylthiouracil) passes into breast milk. If you are breast-feeding and are taking Propyl Thyracil (Propylthiouracil), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
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