Nucala medication

Medications Index

Nucala

Nucala (Mepolizumab) is a monoclonal antibody that belongs to the class of medications called interleukin-5 inhibitors. It is used in addition to other medications to treat a type of Asthma called eosinophilic asthma.

Available form

Injectable, Powder, Injectable

Manufacturer

Glaxosmithkline

Dosage

40mg/0.4ml100mg100mg/1ml

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Drug Information

Index
Dosage
Nucala®

Dosage

For the treatment of eosinophilic asthma, the recommended dose of Nucala (Mepolizumab) for adults and adolescents over 12 years old is 100 mg injected subcutaneously (under the skin) once every 4 weeks. The dose for children ages 6 years to 12 years is 40 mg injected subcutaneously once every 4 weeks.

For the treatment of eosinophilic granulomatosis with polyangiitis, the recommended dose of Nucala (Mepolizumab) for adults is 300 mg injected subcutaneously once every 4 weeks.

Nucala (Mepolizumab) is first given under the supervision of a qualified health care professional in a clinic or doctor's office where side effects, such as a Anaphylaxis (severe allergic reaction), can be treated immediately. If appropriate, you may be trained to give yourself injections of Nucala (Mepolizumab). Do not attempt to prepare or inject Nucala (Mepolizumab) on your own until you completely understand how to mix and inject a dose. If you are having difficulty giving yourself injections, talk to your health care provider.

It is important Nucala (Mepolizumab) be given exactly as recommended by your doctor. If you miss an appointment to receive Nucala (Mepolizumab), contact your doctor as soon as possible to reschedule your appointment. If you are injecting Nucala (Mepolizumab) yourself and you miss a dose, inject it as soon as possible and continue with your regular schedule. If it almost time for your next injection, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

The powder form of Nucala (Mepolizumab) should be stored in its original carton at room temperature. Protect it from light and moisture, and keep it out of the reach of children. The pre-filled autoinjector or pre-filled syringes should be stored in the refrigerator, protected from light. They may be kept at room temperature for up to 7 days if kept in the unopen carton and protected from light. Once the outer carton is removed, Nucala (Mepolizumab) should be injected within 8 hours.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

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