Faslodex (Fulvestrant) belongs to the group of cancer-fighting medications called antineoplastics, and specifically to the type of antineoplastics known as antiestrogens. It treats certain types of Breast Cancer by blocking the effects of the hormone estrogen in the body.
Available form
Injectable
Dosage
Manufacturer
Apotex, Astrazeneca, Auro Pharma, Eugia Pharma, Mylan Pharmaceuticals
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Faslodex (Fulvestrant) is available only as an injection into the muscle of the buttocks. When starting treatment, 500 mg is given as 2 injections of 250 mg, once every 2 weeks for 3 doses. After this, a dose is given every 28 days. Some people can be taught to give Faslodex (Fulvestrant) to themselves. If this is the case, make sure you understand exactly how it is to be injected as instructed by your doctor or nurse. The medication should be a clear, colourless-to-yellow, thick liquid. Do not use the medication if it appears cloudy or discoloured, or if there are particles floating in it.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to use Faslodex (Fulvestrant) exactly as prescribed by your doctor.
If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Faslodex (Fulvestrant) in its original package in the refrigerator, protect it from light, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Faslodex (Fulvestrant). If you are concerned about side effects, discuss the risks and benefits of Faslodex (Fulvestrant) with your doctor.
The following side effects have been reported by at least 1% of people taking Faslodex (Fulvestrant). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Faslodex (Fulvestrant).
Each mL of clear, colourless-to-yellow, viscous liquid for injection contains 50 mg of Faslodex (Fulvestrant). Nonmedicinal ingredients: benzyl alcohol, benzyl benzoate, castor oil, and ethanol 96%.
Do not use this medication if you:
Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Faslodex (Fulvestrant).
HEALTH CANADA ADVISORY
October 18, 2016
Health Canada has issued new restrictions concerning the use of Faslodex (Faslodex (Fulvestrant)). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Driving: Faslodex (Fulvestrant) usually does not make you drowsy or impair your ability to drive or operate machinery. However, it may make some people feel weak. Do not drive or operate machinery if you feel weak.
Kidney function: People with kidney problems or poor kidney function should be closely monitored by their doctor while taking this medication.
Lab test results: Faslodex (Fulvestrant) can cause falsely high amounts of Estradiol (a type of estrogen) in blood tests. This can lead to misinterpretation of whether you are premenopausal or postmenopausal. Make sure all the medical professionals involved in your care know you are taking Faslodex (Fulvestrant).
Liver disease: Faslodex (Fulvestrant) may reduce liver function and can cause liver failure. Liver disease or reduced liver function may cause Faslodex (Fulvestrant) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Faslodex (Fulvestrant), and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Risk of bleeding: Because Faslodex (Fulvestrant) is given by intramuscular (IM) injection, people with an increased risk of bleeding, such as those taking blood thinners (e.g., Warfarin) or those with medical conditions that can cause bleeding, should take extra care when giving themselves an injection.
Pregnancy: Faslodex (Fulvestrant) should not be used during pregnancy. It may cause severe harm to the developing baby if it is used by the mother during children. If you become pregnant while taking Faslodex (Fulvestrant), contact your doctor immediately.
Breast-feeding: It is not known if Faslodex (Fulvestrant) passes into breast milk. If you are a breast-feeding mother and are taking Faslodex (Fulvestrant), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
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