Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Dysport Therapeutic (Abobotulinumtoxin-a). If you are concerned about side effects, discuss the risks and benefits of Dysport Therapeutic (Abobotulinumtoxin-a) with your doctor.

The following side effects have been reported by at least 1% of people taking Dysport Therapeutic (Abobotulinumtoxin-a). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• drooping of the upper eyelid
• face pain
• falls
• flu-like illness
• general feeling of being unwell
• headache
• muscle aches
• muscle weakness at the injection site
• nausea
• pain, tenderness or bruising, burning, swelling, or stinging at the injection site
• redness of the skin
• stuffy nose
• tightness of the skin

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abnormal heart rhythm
• blurred or decreased vision
• burning or prickling sensation
• facial paralysis
• itchy skin
• rash

Stop taking the medication and seek immediate medical attention if any of the following occur:

• breathing problems
• difficulty swallowing
• speech problems
• symptoms of a Anaphylaxis (severe allergic reaction) (e.g., Hives, difficulty breathing, swelling of the throat or mouth)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Dysport Therapeutic (Abobotulinumtoxin-a).

300 units
Each sterile vial contains 300 units of lyophilized abobotulinumtoxinA. Nonmedicinal ingredients: human serum Albumin and lactose.

Dysport Therapeutic

300 units
Each sterile vial contains 300 units of lyophilized abobotulinumtoxinA. Nonmedicinal ingredients: human serum albumin and lactose.

500 units
Each sterile vial contains 500 units of lyophilized abobotulinumtoxinA. Nonmedicinal ingredients: human serum albumin and lactose.

Do not use botulinum toxin type A (Dysport) if you:

• are allergic to botulinum toxin or to any of the ingredients of the medication
• are allergic to cow's milk protein
• have an infection at the site the injection is to be given in
• have Myasthenia Gravis, amyotrophic lateral sclerosis, or Eaton Lambert syndrome

There may be an interaction between botulinum toxin type A (Dysport) and any of the following:

• aclidinium
• aminoglycoside antibiotics (e.g., gentamicin, neomycin, tobramycin, streptomycin)
• antihistamines (e.g., brompheniramine, Diphenhydramine)
• antipsychotics (e.g. Clozapine, Olanzapine, Risperidone)
• atropine
• azelastine
• belladonna
• Benztropine
• clidinium
• Darifenacin
• Flavoxate
• glycopyrrolate
• ipratropium
• Moclobemide
• muscle relaxants (e.g. Cyclobenzaprine, orphenadrine)
• Oxybutynin
• polymyxins (e.g., polymyxin B)
• quinidine
• scopolamine
• Solifenacin
• tiotropium
• Tolterodine
• tricyclic antidepressants (e.g., Amitriptyline, Clomipramine, Imipramine)
• Trospium
• umeclidinium

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Dysport Therapeutic (Abobotulinumtoxin-a). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Dysport Therapeutic (Abobotulinumtoxin-a).

Distant toxin spread: Very rarely, Dysport Therapeutic (Abobotulinumtoxin-a) may spread to other parts of the body other than where it was injected, leading to muscle weakness, difficulty swallowing, pneumonia, speech difficulties, and breathing problems. Distant toxin spread can be fatal. If you develop severe difficulty swallowing, speaking, or breathing while using Dysport Therapeutic (Abobotulinumtoxin-a), contact your doctor immediately. Dysport Therapeutic (Abobotulinumtoxin-a) should be used with caution in people who have pre-existing swallowing, breathing, or nerve problems.

Heart problems: There have been rare reports of heart problems such as irregular heart rhythms and Heart Attack following injection of Dysport Therapeutic (Abobotulinumtoxin-a). If you have heart disease discuss with your doctor how Dysport Therapeutic (Abobotulinumtoxin-a) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Dysport Therapeutic (Abobotulinumtoxin-a), and whether any special monitoring is needed.

Other medical conditions: People with amyotrophic lateral sclerosis, with disorders that produce a depletion of acetylcholine, or disorders that produce peripheral neuromuscular dysfunction should discuss with their doctor how Dysport Therapeutic (Abobotulinumtoxin-a) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Dysport Therapeutic (Abobotulinumtoxin-a), and whether any special monitoring is needed.

Pregnancy: Dysport Therapeutic (Abobotulinumtoxin-a) should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and unborn baby. If you become pregnant while using Dysport Therapeutic (Abobotulinumtoxin-a), contact your doctor immediately.

Breast-feeding: It is not known if Dysport Therapeutic (Abobotulinumtoxin-a) passes into breast milk. If you are a breast-feeding mother and are using Dysport Therapeutic (Abobotulinumtoxin-a), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of Dysport Therapeutic (Abobotulinumtoxin-a) have not been established for children under the age of 18, except for the treatment of lower limb spasticity in children over the age of 2 years.