Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Differin XP (Adapalene).

Area of use: Differin XP (Adapalene) is for external use only. Do not apply to areas near the eyes, lips, angles of the nose, mucous membranes, and open wounds.

Cosmetics: Avoid the use of certain cosmetics that might make your skin worse. Ask a cosmetician for non-comedogenic cosmetics or use water-based makeup. Remove any makeup before applying Differin XP (Adapalene).

Sunlight: Avoid exposure to excessive sunlight (outdoors, sunlamps, and tanning beds). If sun exposure cannot be avoided, use a sunscreen (minimum SPF 30). Waxing as a hair removal method should be avoided.

Pregnancy: Women who are pregnant or considering pregnancy should not use Differin XP (Adapalene). Women who use Differin XP (Adapalene) should ensure that they are using adequate birth control while they are using Differin XP (Adapalene).

Breast-feeding: It is not known if Differin XP (Adapalene) passes into breast milk. If you are a breast-feeding mother and are taking Differin XP (Adapalene), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Differin XP (Adapalene) have not been established for children under the age of 12.

Seniors: The safety and effectiveness of using Differin XP (Adapalene) have not been established for people over the age of 65.