Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Blood pressure: Desmopressin may occasionally cause increases in blood pressure. If you have high blood pressure or heart disease, discuss with your doctor how Desmopressin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed

Cystic Fibrosis: People with cystic fibrosis are more likely to experience low levels of sodium in the body. This can lead to increased side effects with desmopressin. If you have cystic fibrosis, discuss with your doctor how Desmopressin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Desmopressin, and whether any special monitoring is needed.

Fluid and electrolyte balance: Fluid intake should be adjusted in order to reduce the possibility of water retention and low levels of sodium in the blood, especially for very young people and for seniors. People who are dehydrated should wait until their water balance has been adequately restored before taking desmopressin. Seniors should be closely observed for possible water retention and low sodium in the blood due to excessive fluid intake. Talk to your doctor about adjusting the amount of fluid intake that is right for you. For control of nighttime urination, a restricted fluid intake is recommended a few hours before using Desmopressin.

Lactose intolerance: The regular tablet form of Desmopressin contains lactose. If you have galactose intolerance (galactosemia, glucose-galactose malabsorption, or Lapp lactase deficiency) you should not take this formulation. The sublingual tablet formulation does not contain lactose.

Medical conditions: Desmopressin is not effective in controlling excessive urination caused by Kidney Disease, diabetes, psychosomatic conditions, low blood potassium, or high blood calcium.

Short-term illnesses: Many short-term illnesses such as Fever, infections and stomach irritation can cause dehydration. This dehydration may cause complications with the use of desmopressin. Talk to your doctor about how to manage your desmopressin treatment if you develop a short-term illness.

Tolerance: There are reports of changes in response over time, usually when the medication has been used for periods longer than 6 months. Some people may experience decreased responsiveness, while others may experience a shortened duration of effect.

Urinary tract problems: If you have severe bladder or voiding problems, the way your body gets rid of excess water or sodium may be impaired. Discuss with your doctor how Desmopressin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Desmopressin, and whether any special monitoring is needed.

Pregnancy: Desmopressin has been used during pregnancy with no harm reported. However, no controlled studies have been done on its use by pregnant women. Desmopressin should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if desmopressin from desmopressin tablets passes into breast milk. If you are a breast-feeding mother and are taking desmopressin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Children are more likely to experience low sodium levels and fluid build up as a result of consuming too much fluid. Your child’s doctor should closely monitor fluid and sodium levels while your child is taking desmopressin.  

Seniors: Seniors are more likely to experience low sodium levels and fluid build up as a result of consuming too much fluid or decreased kidney function. Your doctor should closely monitor your condition while you are taking desmopressin.