Cisplatin belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as platinum-containing compounds. Cisplatin stops the growth of cancer cells by interfering with the genetic material DNA, which is necessary for cells to multiply.
Available form
Injectable
Manufacturer
Bristol-myers Squibb, Mylan Pharmaceuticals, Sandoz
Dosage
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The recommended dose and dosing schedule of cisplatin varies according to the specific type of cancer being treated, the response to therapy, and the other medications or treatments being used. The dose given is based on body size.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor. Your doctor may decide on a dosage schedule different from that described here.
Cisplatin is available as an intravenous (into the vein) injection. It is usually injected through a specially prepared site on the skin. Cisplatin is most often given as a single injection every 3 to 4 weeks or as one injection (of a smaller dose) daily for 5 days every 3 to 4 weeks.
Very careful handling of Cisplatin is required. Cisplatin should only be given by health care professionals familiar with the use of cancer chemotherapy. It is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.
Note that it is very important to drink plenty of fluids right after your treatment. Your doctor may want you to drink extra fluids while taking Cisplatin in order to help you pass more fluid and protect your kidneys. You should try to drink a glass of water every 1 to 2 hours and empty your bladder regularly for at least 24 hours after your treatment.
It is important to use Cisplatin exactly as recommended by your doctor. If you miss an appointment to receive cisplatin, contact your doctor as soon as possible to reschedule your appointment.
As well as interfering with the genetic material DNA of cancer cells, cisplatin can interfere with some of your body’s normal cells. This can cause a number of side effects. Keep track of any side effects and report them to your doctor as suggested in the section, "What side effects are possible with Cisplatin?"
Cisplatin is stored at room temperature. It should be protected from light and kept out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
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*Actual pricing may differ. Medication is only available by prescription. The cost may be subsidised by your provincial or private health plan.
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